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CSIR-CCMB’s expertise in microbial cultures, genome sequencing and population studies have helped us look into the details of the evolution of SARS-CoV-2 coronavirus in India

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Understanding the airborne-transmission characteristics of SARS-CoV-2

Back in 2020, when SARS-CoV-2 was thought to be spread mainly through contact with the infected individuals, CCMB researchers, along with scientists from IMTech, initiated a study to understand the transmission characteristics of SARS-CoV-2 through the air in indoor and outdoor settings. We analyzed air samples from different areas in hospitals like COVID wards, ICUs, […]

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Culturing coronavirus isolates from India

We have cultured the various strains of coronavirus found in Indian isolates. This includes four strains of SARS-CoV-2. i)       A3i ii)      A2a iii)       N440K variant iv)       B1.1.7 variant Additional cultures are being established.  One of them is a sample from a lion and another […]

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Genome sequencing of SARS-CoV-2 isolates from India

SARS-CoV-2 coronavirus makes errors while replicating its genome. These are called mutations or changes to the genomic sequence that lead to changes in the amino acids at the corresponding positions on the viral proteins. While most new mutations are of little to no consequence, a few may be able to transmit better, escape existing immunity, […]

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Genome/transcriptome profiling of COVID-19 patients in India

One of the most perplexing aspects of SARS-CoV-2 coronavirus infection has been the variable responses among those infected. Disease progression is unpredictable and ranges from asymptomatic, mild infection to life-threatening Acute Respiratory Distress Syndrome (ARDS). Mild infections are characterized by symptoms such as fever and cough, and are usually resolved spontaneously in a majority of […]