Under this agreement, CCMB will use Eyestem’s human lung epithelial cell culture system provided as part of its Anti-Covid screening (ACS) platform to understand the molecular and pathological characteristics of the COVID-19 virus with a view to establishing a rational basis for testing potential drugs in vitro.
Commenting on the development, Dr. Rakesh Mishra, Director of CCMB, said “Culturing the virus outside the human host is a technological challenge that needs to be overcome. Eyestem’s cell culture system expresses the ACE2
receptor and other genes that are key determinants of viral entry and replication. We hope that employing this system will allow the CCMB team led by Dr. Krishnan Harshan to grow the virus predictably and thereby open up the
potential for drug screening and vaccine development strategies”
Dr. Jogin Desai, CEO of Eyestem agreed and remarked “We are honoured to enter into this research collaboration with one of the premier scientific institutes in India. The ACS platform has been developed by Dr. Rajarshi Pal and his team and is a testament to our depth and expertise in cell therapy and disease modelling. We remain hopeful that CCMB will be able to leverage this platform and advance Covid research that will help humanity in India and abroad”
The Centre for Cellular & Molecular Biology (CCMB), a premier research organization in frontier areas of modern biology is an autonmous laboratory under the Council for Scientific and Industrial Research.(CSIR) CCMB has responded to the current crisis and was the first academic laboratory outside ICMR to initiate COVID19 testing and kit validation. In addition, CCMB has intiated a variety of new research projects on SARS-CoV2.
Eyestem Research Private Limited is a cell therapy start-up incubated at the Centre for Cellular and Molecular Platforms, Bangalore. Its vision is to democratize access to cell therapy as well as disease modeling platforms and bring their benefit to a large section of humanity.